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Mouth Infections


What is the herpes simplex virus?
Some people call it a cold sore, others a fever blister, but this annoying and often painful chronic condition is caused by the same virus: herpes simplex. According to the National Institute of Dental Research, eight out of every 10 American adults are infected with this virus. Once infected, a person will have the herpes simplex virus for the rest of his/her life. When inactive, the virus lies dormant in a group of nerve cells. Some people never have any symptoms from the virus, others have periodic outbreaks of infections.

What causes the herpes simplex virus?
Characterized by blister-like lesions that occur over an eight- to 10-day period most often around the lips, oral mucosa, or tongue, the virus is highly contagious and can spread easily by direct skin-to-skin contact. The two most common forms of the virus are herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2). HSV1 is most often associated with infections of the oral cavity, while HSV2 is most often associated with genital herpes infections. However, research suggests that both types of HSV can infect both the mouth and the genitals.

What are canker sores?

Sometimes confused with herpes simplex sores, canker sores are common, small ulcers inside the mouth that are not contagious. Canker sores typically have a white or gray base with a red border, and usually heal within two weeks. Antibacterial mouthrinses and over-the-counter topical anesthetics may help relieve any discomfort. Avoiding hot, spicy, or acidic foods can also help to relieve symptoms.

How can HSV infections be prevented?
Since HSV is transmitted through direct, physical contact, such as kissing and sexual contact, the best method of prevention is to avoid physical contact with the HSV sores when someone is experiencing an outbreak of the disease. However, genital herpes can be contagious without causing any symptoms of the disease, according to the Centers for Disease Control and Prevention.

What are the symptoms of an oral herpes simplex virus infection?
Initial infection of the oral herpes simplex virus may cause no symptoms or may cause severe flu-like symptoms with mouth ulcers. In recurring infections, sores tend to erupt in the same area (some patients never have any more symptoms beyond the initial infection). The following are the most common symptoms of an oral herpes simplex virus infection. However, each individual may experience symptoms differently. The progression of symptoms may include:

  • Symptoms may begin with redness, swelling, heat, and pain in the area where the infection will erupt.
  • Painful, fluid-filled blisters may appear on the lips or under the nose. These blisters are highly contagious.
  • The blisters leak fluids and become sores.
  • After approximately four days, the sores start to crust over and heal.

The symptoms of an oral herpes simplex virus may resemble other conditions or medical problems. Always consult your physician for a diagnosis.

How is an oral HSV diagnosed?
Herpes simplex virus is difficult to diagnose. Often confused with many other infections, such as allergic reactions, the herpes simplex virus can only be confirmed with a virus culture, blood test, or biopsy. However, the location of the blisters usually is, to a physician, a positive indication of an infection.

Treatment for oral HSV infections:
Treatment depends on the severity of symptoms of the HSV virus. Specific treatment for HSV infection will be determined by your physician(s) based on:

  • your overall health and medical history
  • extent of the disease
  • your tolerance for specific medications, procedures, or therapies
  • expectations for the course of the disease
  • your opinion or preference

Treatment may involve:

  • keeping the infected area clean and dry
  • antibiotic treatment for any bacterial infections
  • topical antiviral creams


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